名词解释题体细胞基因治疗(somatic cell gene therapy)

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名词解释题
体细胞基因治疗(somatic cell gene therapy)

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3.共用题干 Stem Cell Therapy May Help Repair the HeartAccording to scientists in the USA,stem cell therapy may one day be able to repair the hearts of people with heart failure.Researchers at Pittsburgh University School of Medicine examined 20 patients who had severe heart failure and were going to have surgery.They injected stem cells into the parts of their hearts that were damaged.They then compared their hearts with those of people who had undergone surgery without having the stem cells injected into them(they had also suffered from severe heart failure).The patients who had had the stem cells injected had hearts that were able to pump(用泵抽运) more blood than the others.According to Professor Robert Kormos,one of the researchers,these results could revolutionize heart treatment.Although previous studies had indicated that there might be a benefit,this is the first study that has actually proved that stem cell therapy can help thefailing heart work better.All the patients in this study had hearts that could not pump blood properly.The scientists measured their ejection fraction(射血分数).This is a measure of heart performance;you measure how much blood is being pumped out by the left ventricle(心室).Healthy people's ejection fraction is about 55%.These patients had ejection fraction ofunder 35%. They all had by-pass surgery(搭桥手术)performed on them. Some of the patients had stem cells taken from their hip bones and injected into 25-30 sites in the damaged heart muscle.Six months later their ejection fraction rate was 46.1%while those who just had surgery but no stem cell injections averaged 37. 2%.No side effects were reported.Heart failure is a common problem all over the world.In the UK alone about 650, 000 people suffer from heart failure every year. As the number of people suffering from heart failure increases in the world in general these findings are particularly significant.Current treatments relieve the symptoms.This new stem cell therapy actually repairs the damaged muscle in the heart and has the potential of curing the disease. The 20 patients had stem cell injections instead of surgery.A:Right B:Wrong C:Not mentioned

更多“体细胞基因治疗(somatic cell gene therapy)”相关问题
  • 第1题:

    共用题干
    Stem Cell Therapy May Help Repair the Heart
    According to scientists in the USA,stem cell therapy may one day be able to repair the
    hearts of people with heart failure.Researchers at Pittsburgh University School of Medicine
    examined 20 patients who had severe heart failure and were going to have surgery.
    They injected stem cells into the parts of their hearts that were damaged.They then
    compared their hearts with those of people who had undergone surgery without having the
    stem cells injected into them(they had also suffered from severe heart failure).The
    patients who had had the stem cells injected had hearts that were able to pump(用泵抽运)
    more blood than the others.
    According to Professor Robert Kormos,one of the researchers,these results could
    revolutionize heart treatment.Although previous studies had indicated that there might be a
    benefit,this is the first study that has actually proved that stem cell therapy can help the
    failing heart work better.
    All the patients in this study had hearts that could not pump blood properly.The
    scientists measured their ejection fraction(射血分数).This is a measure of heart
    performance;you measure how much blood is being pumped out by the left ventricle(心
    室).
    Healthy people's ejection fraction is about 55%.These patients had ejection fraction of
    under 35%. They all had by-pass surgery(搭桥手术)performed on them. Some of the
    patients had stem cells taken from their hip bones and injected into 25-30 sites in the
    damaged heart muscle.Six months later their ejection fraction rate was 46.1%while those
    who just had surgery but no stem cell injections averaged 37. 2%.
    No side effects were reported.
    Heart failure is a common problem all over the world.In the UK alone about 650, 000
    people suffer from heart failure every year. As the number of people suffering from heart
    failure increases in the world in general these findings are particularly significant.
    Current treatments relieve the symptoms.This new stem cell therapy actually repairs
    the damaged muscle in the heart and has the potential of curing the disease.

    Stem cell therapy seems to have great prospects.
    A:Right
    B:Wrong
    C:Not mentioned

    答案:A
    解析:

  • 第2题:


    Which of the following is TRUE according to the text?( )

    A.The principle of gene therapy is applicable to that of cloning.
    B.The isolation of stem cells is too difficult to be feasible.
    C.It is reasonable for all body instructions to be activated.
    D.Cloned animals will eventually take control of the world.

    答案:A
    解析:

  • 第3题:

    基因治疗中,基因转移的靶细胞有生殖细胞和体细胞两类。


    正确答案:错误

  • 第4题:

    基因治疗是人类疾病治疗的一种崭新手段,下列有关叙述中不正确的是()

    • A、基因治疗可使一些人类遗传病得到根治
    • B、基因治疗是一种利用基因工程产品治疗人类疾病的方法
    • C、以正常基因替换致病基因属于基因治疗的一种方法
    • D、基因治疗的靶细胞可以是体细胞和生殖细胞

    正确答案:B

  • 第5题:

    锥体细胞(pyramidal cell)


    正确答案:为大脑皮质内的一种神经元,其胞体形似锥体,其尖端发出一条较粗的顶树突,伸向皮质表面,沿途发出许多小分支。胞体还向周围发出一些水平走向的基树突。轴突则从胞体的底部发出。锥体细胞是大脑皮质的主要传出神经元。

  • 第6题:

    基因对基因学说(gene-for-gene theory)


    正确答案: 对应于寄主方面的每一个决定抗病性的基因,病原物方面也存在一个决定致病性的基因。反之,对应于病原物方面的每一个决定致病性的基因,寄主方面也存在一个决定抗病性的基因。

  • 第7题:

    体细胞基因治疗(somatic cell gene therapy)


    正确答案:是指将正常基因转移到体细胞,使之表达基因产物,以达到治疗目的。这种方法的理想措施是将外源正常基因导入靶体细胞内染色体特定基因座位,用健康的基因确切地替换异常的基因,使其发挥治疗作用,同时还须减少随机插入引起新的基因突变的可能性。

  • 第8题:

    同源重组(homologous recombination)与胚胎干细胞(embryonic stem cell)结合起来,创造了基因打靶技术(gene targeting),并得到基因敲除模型,获得了()年的诺贝尔奖

    • A、2006
    • B、2007
    • C、2008
    • D、2009

    正确答案:B

  • 第9题:

    名词解释题
    somatic stem cell (成体干细胞)

    正确答案: 是一类成熟较慢但能自我维持增殖的未分化的细胞,这种细胞存在于各种组织的特定位置上,一旦需要,这些细胞便可按发育途径,先进行细胞分裂,然后经过分化产生出另外一群具有有限分裂能力的细胞群。
    成体干细胞的发育等级较低,是多能或单能干细胞。造血干细胞(hematopoietic stem cell,HSC)和骨髓间质干细胞(mesenhymal stem cell)是熟知的成体干细胞。
    解析: 暂无解析

  • 第10题:

    单选题
    目前进行的基因治疗属于()。
    A

    生殖细胞基因治疗

    B

    原核细胞基因治疗

    C

    胎儿基因治疗

    D

    体细胞基因治疗


    正确答案: B
    解析: 暂无解析

  • 第11题:

    名词解释题
    基因治疗(gene therapy)

    正确答案: 基因治疗是指应用重组DNA技术,更换、修正或替代患者细胞中有缺陷的致病基因,恢复这些基因的正常功能,以达到治疗遗传病的目的。
    解析: 暂无解析

  • 第12题:

    判断题
    基因治疗中,基因转移的靶细胞有生殖细胞和体细胞两类。
    A

    B


    正确答案:
    解析: 暂无解析

  • 第13题:


    Which of the following is TRUE according to the text?( )

    A.The principle of gene therapy is applicable to that of cloning
    B.The isolation of stem cells is too difficult to be feasible
    C.It is reasonable for all body instructions to be activated
    D.Cloned animals will eventually take control of the world

    答案:A
    解析:

  • 第14题:

    脊髓损伤基因治疗的受体细胞应符合什么标准?目前用于研究的主要有哪些细胞?


    正确答案:在脊髓损伤治疗中,由于受体细胞要植入脊髓内,因此所用受体细胞应当符合以下标准:
    [1]容易获取和繁殖;
    [2]移植后能长期存活且能继续分裂和具有活力;
    [3]无免疫源性及形成肿瘤的危险。目前已用于脊髓损伤基因治疗研究的有雪旺氏细胞、成纤维细胞、骨髓间充质干细胞和肌母细胞等。

  • 第15题:

    目前进行的基因治疗属于()。

    • A、生殖细胞基因治疗
    • B、原核细胞基因治疗
    • C、胎儿基因治疗
    • D、体细胞基因治疗

    正确答案:D

  • 第16题:

    关于应用基因工程治疗人类遗传病的叙述,不正确的是()

    • A、基因治疗可以有效地改善患者生理状况,其操作对象是基因
    • B、进行基因治疗时,基因的受体细胞是受精卵
    • C、基因治疗并不是对患者体内细胞的缺陷基因进行改造
    • D、基因治疗时可只对患者部分细胞输入正常基因

    正确答案:B

  • 第17题:

    细胞胚胎发生(somatic embryogenesis)


    正确答案: 是指植物体细胞通过无性繁殖产生一种类似于合子胚的结构来实现植株再生的过程。

  • 第18题:

    基因治疗(gene therapy)


    正确答案:基因治疗是指应用重组DNA技术,更换、修正或替代患者细胞中有缺陷的致病基因,恢复这些基因的正常功能,以达到治疗遗传病的目的。

  • 第19题:

    ()是指通过重构或纠正异常遗传物质或者干扰引起疾病的过程,来纠正或预防疾病。

    • A、增强性基因治疗
    • B、肿瘤性基因治疗
    • C、治疗性基因治疗
    • D、体细胞基因治疗

    正确答案:C

  • 第20题:

    单选题
    将正常基因转移到患者的生殖细胞中而使之发育成一个正常的个体称为()。
    A

    体细胞基因治疗

    B

    生殖细胞基因治疗

    C

    胚胎细胞的基因治疗

    D

    胚胎组织细胞基因治疗

    E

    胎儿的基因治疗


    正确答案: B
    解析: 暂无解析

  • 第21题:

    名词解释题
    regulatory gene;regulator gene (调节基因)

    正确答案: 控制编码RNA基因或蛋白质基因表达的基因。如编码激活蛋白或阻遏蛋白的基因。
    解析: 暂无解析

  • 第22题:

    名词解释题
    细胞胚胎发生(somatic embryogenesis)

    正确答案: 是指植物体细胞通过无性繁殖产生一种类似于合子胚的结构来实现植株再生的过程。
    解析: 暂无解析

  • 第23题:

    单选题
    ()是指通过重构或纠正异常遗传物质或者干扰引起疾病的过程,来纠正或预防疾病。
    A

    增强性基因治疗

    B

    肿瘤性基因治疗

    C

    治疗性基因治疗

    D

    体细胞基因治疗


    正确答案: C
    解析: 暂无解析